The Dasen Lab

 

D'Elia KP, Hameedy H, Goldblatt D, Frazel P, Kriese M, Zhu Y, Hamling KR, Kawakami K, Liddelow SA, Schoppik D, Dasen JS. Determinants of motor neuron functional subtypes important for locomotor speed. Cell Rep. 2023 Sep 6;42(9):113049

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Sawai A, Pfennig S, Bulajic M, Miller A, Khodadadi-Jamayran A, Mazzoni EO, Dasen JS. 2022. PCRC1 Sustains the Integrity of Neural Fate in the Absence of PRC2 Function. eLife2022;11:e72769 

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Shin MM, Catela C, Dasen JS. 2020. Intrinsic Control of Neuronal Diversity and Synaptic Specificity in a Proprioceptive Circuit. eLife 2020;9:e56374

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Baek M, Menon V, Jessell TM, Hantman AW, Dasen JS. 2019. Molecular Logic of Spinocerebellar Tract Neuron Diversity and Connectivity. Cell Rep. 27, 2620-2635.

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Jung H, Baek M, D’Elia KP, Boisvert B, Tay B-H, Currie P, Venkatesh B, Brown SM, Heguy A, Schoppik D, Dasen JS. 2017. The Ancient Origins of Neural Substrates for Land Walking. Cell 172, 667-682.

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Baek M, Pivetta C, Liu J-P, Arber A, Dasen JS. 2017. Columnar-Intrinsic Cues Shape Premotor Input Specificity in Locomotor Circuits. Cell Reports 21, 867-877.

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Hanley O, Zewdu R, Cohen LJ, Jung H, Lacombe J, Philippidou P, Lee DH, Selleri L, Dasen JS. 2016. Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns. Neuron 91, 1005-20.

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Catela C, Shin MM, Lee DH, Dasen JS. 2016. Hox Proteins Coordinate Motor Neuron Specification and Connectivity Programs Through Ret/Gfrα Genes. Cell Reports 14,1901-15.

 

Jung H, Mazzoni EO, Soshnikova N, Hanley O, Venkatesh B, Duboule D, Dasen JS. 2014. Evolving Hox Activity Profiles Govern Diversity in Locomotor Systems. Developmental Cell 29, 171-187.

 

Lacombe J, Hanley O, Jung H, Philippidou P, Grinstein J, Dasen JS. 2013. Genetic and Functional Modularity of Hox Activities in the Specification of Limb-Innervating Motor Neurons. PLOS Genetics, 9, 1-15.

 

Philippidou P, Walsh CM, Aubin J, Jeannotte L, Dasen JS. 2012. Sustained Hox5 Gene Activity is Required for Respiratory Motor Neuron Development. Nature Neuroscience 15, 1636-1644.

 

Golden MG, Dasen JS. 2012. Polycomb Repressive Complex-1 Activities Determine the Columnar Organization of Motor Neurons. Genes and Development 26, 2236-2250.

 

Jung H, Lacombe J, Mazzoni EO, Liem Jr KF, Grinstein J, Mahony S, Mukhopadhyay D, Gifford DK, Young RA, Anderson KV, Wichterle H, Dasen JS. 2010. Global Control of Motor Neuron Topography Mediated by the Repressive Actions of a Single Hox Gene. Neuron 67, 781-796.

 

Peljto M, Dasen JS, Mazzoni EO, Jessell TM, Wichterle H. 2010. Functional Diversity of ESC-Derived Motor Neuron Subtypes Revealed through Intraspinal Transplantation. Cell Stem Cell 7, 355-366.